A Nonselective Cation Channel in Adult Alveolar Epithelial Cells

A Nonselective Cation Channel in Adult Alveolar Epithelial Cells

OBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membra...

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Main Authors: Beverley A Orser, Jeffrey D Edelson
Format: Article
Language:English
Published: Hindawi Limited 1994-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1994/357537
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spelling doaj-f2acc7cb82414884aef4a82e688f46a72021-07-02T02:54:25ZengHindawi LimitedCanadian Respiratory Journal1198-22411994-01-011212913610.1155/1994/357537A Nonselective Cation Channel in Adult Alveolar Epithelial CellsBeverley A Orser0Jeffrey D Edelson1Department of Anaesthesia, Sunnybrook Health Science Centre, Department of Physiology, University of Toronto, Toronto, Ontario, CanadaDepartment of Anaesthesia, Sunnybrook Health Science Centre, Department of Physiology, University of Toronto, Toronto, Ontario, CanadaOBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membrane. A cation channel, previously identified in fetal alveolar epithe lium, may represent one of several pathways which regulate apical-basal transepithelial Na+ flux. The purpose of this study was to determine if cation channels are also present in adult alveolar epithelial cells.http://dx.doi.org/10.1155/1994/357537
collection DOAJ
language English
format Article
sources DOAJ
author Beverley A Orser
Jeffrey D Edelson
spellingShingle Beverley A Orser
Jeffrey D Edelson
A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
Canadian Respiratory Journal
author_facet Beverley A Orser
Jeffrey D Edelson
author_sort Beverley A Orser
title A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
title_short A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
title_full A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
title_fullStr A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
title_full_unstemmed A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
title_sort nonselective cation channel in adult alveolar epithelial cells
publisher Hindawi Limited
series Canadian Respiratory Journal
issn 1198-2241
publishDate 1994-01-01
description OBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membrane. A cation channel, previously identified in fetal alveolar epithe lium, may represent one of several pathways which regulate apical-basal transepithelial Na+ flux. The purpose of this study was to determine if cation channels are also present in adult alveolar epithelial cells.
url http://dx.doi.org/10.1155/1994/357537
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AT beverleyaorser nonselectivecationchannelinadultalveolarepithelialcells
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