Protein Binding Detection Using On-Chip Silicon Gratings

We demonstrate a silicon gratings-based biosensor to detect functionalized protein binding on its surface. The designed silicon gratings have sensitivities up to 197 nm/RIU in detecting refractive index change and 1.61 nm per nanometer of thickness change of bio-material on the surface of silicon gr...

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Bibliographic Details
Main Authors: Jayshri Sabarinathan, Anil Kumar Mudraboyina
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/11/12/11295/