Immunological blocking of spermidine‐mediated host–pathogen communication provides effective control against Pseudomonas aeruginosa infection

Summary Pseudomonas aeruginosa is known to cause life‐threatening infections. The previous studies showed that the type III secretion system (T3SS) of this pathogen is a key virulence determinant, which is activated by polyamines signals spermidine (Spd) and spermine (Spm) from mammalian host. To te...

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Bibliographic Details
Main Authors: Jianhe Wang, Jing Wang, Lian‐Hui Zhang
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.13279