Functional paralysis of human natural killer cells by alphaherpesviruses.

Natural killer (NK) cells are implicated as important anti-viral immune effectors in varicella zoster virus (VZV) infection. VZV can productively infect human NK cells, yet it is unknown how, or if, VZV can directly affect NK cell function. Here we demonstrate that VZV potently impairs the ability o...

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Bibliographic Details
Main Authors: Tessa Mollie Campbell, Brian Patrick McSharry, Megan Steain, Tiffany Ann Russell, David Carl Tscharke, Jarrod John Kennedy, Barry Slobedman, Allison Abendroth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007784