A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review

We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of stand...

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Main Authors: Pablo Manresa, Fabián Tarín, María Niveiro, María Tasso, Olga Alda, Francisco López, Héctor Sarmiento, José J. Verdú, Francisco De Paz, Silvia López, María Del Cañizo, Esperanza Such, Eva Barragán, Fernanda Martirena
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/4/12/113
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spelling doaj-f2936b98513e4a2bb90e53d482d603232021-04-02T09:58:57ZengMDPI AGChildren2227-90672017-12-0141211310.3390/children4120113children4120113A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature ReviewPablo Manresa0Fabián Tarín1María Niveiro2María Tasso3Olga Alda4Francisco López5Héctor Sarmiento6José J. Verdú7Francisco De Paz8Silvia López9María Del Cañizo10Esperanza Such11Eva Barragán12Fernanda Martirena13Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Anatomic Pathology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, SpainDepartment of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, SpainDepartment of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, SpainDepartment of Hematology, Hospital de Elda, 03600 Elda, Alicante, SpainWe describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue.https://www.mdpi.com/2227-9067/4/12/113red blood cell disordersleukemiasacutehematologyimmunophenotypesarcomasincluding soft tissuenon-rhabdoid
collection DOAJ
language English
format Article
sources DOAJ
author Pablo Manresa
Fabián Tarín
María Niveiro
María Tasso
Olga Alda
Francisco López
Héctor Sarmiento
José J. Verdú
Francisco De Paz
Silvia López
María Del Cañizo
Esperanza Such
Eva Barragán
Fernanda Martirena
spellingShingle Pablo Manresa
Fabián Tarín
María Niveiro
María Tasso
Olga Alda
Francisco López
Héctor Sarmiento
José J. Verdú
Francisco De Paz
Silvia López
María Del Cañizo
Esperanza Such
Eva Barragán
Fernanda Martirena
A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
Children
red blood cell disorders
leukemias
acute
hematology
immunophenotype
sarcomas
including soft tissue
non-rhabdoid
author_facet Pablo Manresa
Fabián Tarín
María Niveiro
María Tasso
Olga Alda
Francisco López
Héctor Sarmiento
José J. Verdú
Francisco De Paz
Silvia López
María Del Cañizo
Esperanza Such
Eva Barragán
Fernanda Martirena
author_sort Pablo Manresa
title A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
title_short A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
title_full A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
title_fullStr A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
title_full_unstemmed A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
title_sort rare case of pure erythroid sarcoma in a pediatric patient: case report and literature review
publisher MDPI AG
series Children
issn 2227-9067
publishDate 2017-12-01
description We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue.
topic red blood cell disorders
leukemias
acute
hematology
immunophenotype
sarcomas
including soft tissue
non-rhabdoid
url https://www.mdpi.com/2227-9067/4/12/113
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