Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage

Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage

In patients with liver cirrhosis, minimal hepatic encephalopathy (MHE) is triggered by a shift in peripheral inflammation, promoting lymphocyte infiltration into the brain. Rifaximin improves neurological function in MHE by normalizing peripheral inflammation. Patients who died with steatohepatitis...

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Bibliographic Details
Main Authors: Tiziano Balzano, Paola Leone, Gergana Ivaylova, M. Carmen Castro, Lestteriel Reyes, Chusé Ramón, Michele Malaguarnera, Marta Llansola, Vicente Felipo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
liver disease
minimal hepatic encephalopathy
chemokines
neuroinflammation
neurotransmission
cerebellum
Online Access:https://www.mdpi.com/2227-9059/9/8/1002

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