Neddylation, an Emerging Mechanism Regulating Cardiac Development and Function

Neddylation, an Emerging Mechanism Regulating Cardiac Development and Function

Defects in protein quality control have been increasingly recognized as pathogenic factors in the development of heart failure, a persistent devastating disease lacking efficacious therapies. Ubiquitin and ubiquitin-like proteins, a family of post-translational modifying polypeptides, play important...

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Bibliographic Details
Main Authors: Jie Li, Jianqiu Zou, Rodney Littlejohn, Jinbao Liu, Huabo Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Physiology
Subjects:
NEDD8 (neural precursor cell expressed developmentally down-regulated 8)
Ubiquitin-like protein
Neddylation
cardiomyopathy
Heart Failure
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.612927/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.612927/full

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