Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range

Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range

Abstract The main diffusion barrier for drugs penetrating through the skin is located in the intercellular lipid matrix in the upper layer of the skin, the stratum corneum (SC). The main lipid classes in the SC are ceramides (CER), free fatty acids (FFA) and cholesterol (CHOL). The lipids in SC are...

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Bibliographic Details
Main Authors: J.A. Bouwstra, G.S. Gooris, F.E.R. Dubbelaar, M. Ponec
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Journal of Lipid Research
Subjects:
stratum corneum
ceramides
phase behavior
X-ray diffraction
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321052

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http://www.sciencedirect.com/science/article/pii/S0022227520321052

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