Ex vivo analysis of human memory B lymphocytes specific for A and B influenza hemagglutinin by polychromatic flow-cytometry.

Ex vivo analysis of human memory B lymphocytes specific for A and B influenza hemagglutinin by polychromatic flow-cytometry.

Understanding the impact that human memory B-cells (MBC), primed by previous infections or vaccination, exert on neutralizing antibody responses against drifted influenza hemagglutinin (HA) is key to design best protective vaccines. A major obstacle to these studies is the lack of practical tools to...

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Bibliographic Details
Main Authors: Monia Bardelli, Liliana Alleri, Francesca Angiolini, Francesca Buricchi, Simona Tavarini, Chiara Sammicheli, Sandra Nuti, Elena Degl'Innocenti, Isabelle Isnardi, Elena Fragapane, Giuseppe Del Giudice, Flora Castellino, Grazia Galli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744578?pdf=render

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