Haplotypes composed of minor frequency single nucleotide polymorphisms of the TNF gene protect from progression into sepsis: A study using the new sepsis classification

Haplotypes composed of minor frequency single nucleotide polymorphisms of the TNF gene protect from progression into sepsis: A study using the new sepsis classification

Objectives: Several articles have provided conflicting results regarding the role of single nucleotide polymorphisms (SNPs) in the promoter region of the TNF gene in susceptibility to sepsis. Former articles have been based on previous definitions of sepsis. This study investigated the influence of...

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Bibliographic Details
Main Authors: Theodoros Retsas, Klaus Huse, Lazaros-Dimitrios Lazaridis, Niki Karampela, Michael Bauer, Matthias Platzer, Virginia Kolonia, Eirini Papageorgiou, Evangelos J. Giamarellos-Bourboulis, George Dimopoulos
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:International Journal of Infectious Diseases
Subjects:
Tumour necrosis factor alpha
Single nucleotide polymorphism
Sepsis
Haplotype
Online Access:http://www.sciencedirect.com/science/article/pii/S120197121730320X

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