Rationale and Design of a Statewide Cohort to examine efficient resource utilization for patients with Intracerebral hemorrhage (EnRICH)

• Main Authors: Farhaan S. Vahidy, Ellie G. Meyer, Arvind B. Bambhroliya, Jennifer R. Meeks, Charles E. Begley, Tzu-Ching Wu, Jon E. Tyson, Charles C. Miller, Ritvij Bowry, Wamda O. Ahmed, Gretchel A. Gealogo, Louise D. McCullough, Steven Warach, Sean I. Savitz
• Format: Article
• Language: English
• Published: BMC 2018-03-01
• Series: BMC Neurology
• Subjects: Stroke; Intracerebral hemorrhage; Patient-centered outcomes; Quality of life; Readmission rate; Mortality
• Online Access: http://link.springer.com/article/10.1186/s12883-018-1036-1

Abstract Background Intracerebral hemorrhage is a devastating disease with no specific treatment modalities. A significant proportion of patients with intracerebral hemorrhage are transferred to large stroke treatment centers, such as Comprehensive Stroke Centers, because of perceived need for higher level of care. However, evidence of improvement in patient-centered outcomes for these patients treated at larger stroke treatment centers as compared to community hospitals is lacking. Methods / design “Efficient Resource Utilization for Patients with Intracerebral Hemorrhage (EnRICH)” is a prospective, multisite, state-wide, cohort study designed to assess the impact of level of care on long-term patient-centered outcomes for patients with primary / non-traumatic intracerebral hemorrhage. The study is funded by the Texas state legislature via the Lone Star Stroke Research Consortium. It is being implemented via major hub hospitals in large metropolitan cities across the state of Texas. Each hub has an extensive network of “spoke” hospitals, which are connected to the hub via traditional clinical and administrative arrangements, or by telemedicine technologies. This infrastructure provides a unique opportunity to track outcomes for intracerebral hemorrhage patients managed across a health system at various levels of care. Eligible patients are enrolled during hospitalization and are followed for functional, quality of life, cognitive, resource utilization, and dependency outcomes at 30 and 90 days post discharge. As a secondary aim, an economic analysis of the incremental cost-effectiveness of treating intracerebral hemorrhage patients at higher levels of care will be conducted. Discussion Findings from EnRICH will provide much needed evidence of the effectiveness and efficiency of regionalized care for intracerebral hemorrhage patients. Such evidence is required to inform policy and streamline clinical decision-making.