Interleukin (IL)-6: A Friend or Foe of Pregnancy and Parturition? Evidence From Functional Studies in Fetal Membrane Cells

Interleukin (IL)-6: A Friend or Foe of Pregnancy and Parturition? Evidence From Functional Studies in Fetal Membrane Cells

ObjectiveProtection of the fetus within the amniotic sac is primarily attained by remodeling fetal membrane (amniochorion) cells through cyclic epithelial to mesenchymal and mesenchymal to epithelial (EMT and MET) transitions. Endocrine and paracrine factors regulate EMT and MET during pregnancy. At...

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Bibliographic Details
Main Authors: Chasey Omere, Lauren Richardson, George R. Saade, Elizabeth A. Bonney, Talar Kechichian, Ramkumar Menon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
amniotic epithelial cells (AECs)
cytokines
EMT
inflammation
fetal membranes
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00891/full

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