Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury

Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury

Abstract The circadian clock is closely related to the development of diabetes mellitus and cardiovascular disease, and disruption of the circadian clock exacerbates myocardial ischaemia/reperfusion injury (MI/RI). HDAC3 is a key component of the circadian negative feedback loop that controls the ex...

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Bibliographic Details
Main Authors: Zhen Qiu, Hao Ming, Shaoqing Lei, Bin Zhou, Bo Zhao, Yanli Yu, Rui Xue, Zhongyuan Xia
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03295-y

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https://doi.org/10.1038/s41419-020-03295-y

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