| Summary: | Introduction: Knee osteoarthritis (KOA) is the most common degenerative joint disease resulting in bone pain and disability. The aim of current study is to determine diet quality by healthy eating index (HEI)-2015 in association with pain and functional status among a sample of participants with primary knee OA. Methods: In this cross-sectional study, 220 patients with knee OA were recruited via convenience sampling in the outpatient clinics of Tabriz University of Medical Sciences between April and September 2018. The HEI-2015 score was calculated from dietary data collected using a Food Frequency Questionnaire (FFQ). Visual analogue scale, Western Ontario and McMaster Universities Osteoarthritis Index and the SF36 quality of life (QoL) questionnaire were applied to measure the pain intensity, functional status and QoL in the participants, respectively. Participants were categorized based on the quintile cutoff points of HEI score including 42-62, 63-69, 70-75, 76-78 and 79-100. Results: The mean score of HEI was 70.62±10.18 (range: 42–89). Participants with greater HEI- 2015 scores had higher total energy intake (P=0.008) and greater dietary intake of carbohydrates (P=0.01), protein (P=0.009), monounsaturated fatty acids (P=0.01), polyunsaturated fatty acids (P=0.007) and fiber (P=0.009) and lower intake of saturated fatty acids (P=0.005). Participants in higher quintiles of HEI had significantly lower pain intensity (P=0.001) and higher scores of physical function (P=0.001), pain (P=0.001) and role limitation due to physical problems (P=0.005) subscales of SF-36 QoL questionnaire in comparison with participants in lower quintiles of HEI-2015. Conclusion: The HEI-2015 score is associated with pain intensity and two domain of QoL in patients with knee OA.
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