Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer
Tumours that are deficient in mismatch-repair genes should, in theory, have higher evolvability. Here, the authors explore this theory in gastro-oesophageal tumours.
Main Authors: | Katharina von Loga, Andrew Woolston, Marco Punta, Louise J. Barber, Beatrice Griffiths, Maria Semiannikova, Georgia Spain, Benjamin Challoner, Kerry Fenwick, Ronald Simon, Andreas Marx, Guido Sauter, Stefano Lise, Nik Matthews, Marco Gerlinger |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-13915-7 |
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