Characteristics of Pan-Cancer Patients With Ultrahigh Tumor Mutation Burden

Characteristics of Pan-Cancer Patients With Ultrahigh Tumor Mutation Burden

BackgroundTumor mutation burden has been proven to be a good predictor for the efficacy of immunotherapy, especially in patients with hypermutation. However, most research focused on the analysis of hypermutation in individual tumors, and there is a lack of integrated research on the hypermutation a...

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Bibliographic Details
Main Authors: Hong Yuan, Jun Ji, Min Shi, Yan Shi, Jing Liu, Junwei Wu, Chen Yang, Wenqi Xi, Qingyuan Li, Wei Zhu, Jingjie Li, Xiaoli Gong, Jun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
pan-cancer
hypermutation
tumor mutation burden
mismatch repair
polymerase
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.682017/full

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