Physiological Roles of the Rapidly Activated Delayed Rectifier K<sup>+</sup> Current in Adult Mouse Heart Primary Pacemaker Activity

Physiological Roles of the Rapidly Activated Delayed Rectifier K<sup>+</sup> Current in Adult Mouse Heart Primary Pacemaker Activity

Robust, spontaneous pacemaker activity originating in the sinoatrial node (SAN) of the heart is essential for cardiovascular function. Anatomical, electrophysiological, and molecular methods as well as mathematical modeling approaches have quite thoroughly characterized the transmembrane fluxes of N...

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Bibliographic Details
Main Authors:	Wei Hu, Robert B. Clark, Wayne R. Giles, Erwin Shibata, Henggui Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	International Journal of Molecular Sciences
Subjects:	mouse heart sino-atrial node SAN mathematical modeling spontaneous pacemaker activity repolarization
Online Access:	https://www.mdpi.com/1422-0067/22/9/4761

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