In Silico Investigation of Potential TRAF6 Inhibitor from Traditional Chinese Medicine against Cancers

It has been indicated that tumor necrosis factor receptor-associated factor-6 (TRAF6) will upregulate the expression of hypoxia-inducible factor-1α (HIF-1α) and promote tumor angiogenesis. TRAF6 proteins can be treated as drug target proteins for a differentiation therapy against cancers. As structu...

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Bibliographic Details
Main Authors: Kuan-Chung Chen, Wen-Yuan Lee, Hsin-Yi Chen, Calvin Yu-Chian Chen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/429486