Prevalence of Extensively Drug-Resistant Tuberculosis: a Descriptive Study

• Main Authors: O. A. Pasechnik, A. A. Zimoglyad, I. V. Yarusova, S. V. Vitriv, A. I. Blokh
• Format: Article
• Language: Russian
• Published: Numikom LLC 2018-09-01
• Series: Эпидемиология и вакцинопрофилактика
• Subjects: tuberculosis; prevalence; multi drug resistance; extensively drug-resistant
• Online Access: https://www.epidemvac.ru/jour/article/view/554
• ISSN: 2073-3046; 2619-0494

Background. Extensively drug-resistant tuberculosis (XDR-TB) is a threat to community health. Goal. The estimation of the prevalence of extensively drug-resistant tuberculosis in Omsk region, along with the clinical and epidemiological description of patients with XDRTB. Methodology. A retrospective descriptive epidemiologic research of tuberculosis morbidity in Omsk region in 2006–2017 was conducted.Results. The prevalence of extensively drug-resistant tuberculosis in Omsk region in 2006–2017 was stable at 35.6 per 100ths population with Tinc.=1.0%. The prevalence of extensively drug-resistant tuberculosis in Omsk region was 13.6 per 100ths population (n = 267). Among patients with XDR-TB the majority was of young working age 25–44 years (63.2%), male gender (80.9%), officially unemployed (75.6%), ill for at least 3 years (57.0%), suffering from infiltrative pulmonary tuberculosis (69.2%) and HIV-infected (31.8%). The resistance to seven first and second line antituberculosis drugs was found in 10.1% of patients with XDR-TB. Conclusions. The optimisation of approaches to the organization of additional measures for the prevention of extensively drug-resistant tuberculosis is needed.