Probing Enhanced Cytochrome P450 2B1/2 Activity in Rat Hepatocyte Spheroids through Confocal Laser Scanning Microscopy

Probing Enhanced Cytochrome P450 2B1/2 Activity in Rat Hepatocyte Spheroids through Confocal Laser Scanning Microscopy

Cytochrome P450 (CYP450) enzymes are essential for xenobiotic metabolism. Although CYP450s are found in many tissues, CYP2B1/2 are primarily expressed in the rat liver. The constitutive expression in vivo of CYP2B1/2 is low but it is induced in the presence of various drugs such as phenobarbital (PB...

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Bibliographic Details
Main Authors:	Emmanouhl S. Tzanakakis, Chang-Chun Hsiao, Taku Matsushita, Rory P. Remmel, Wei-Shou Hu
Format:	Article
Language:	English
Published:	SAGE Publishing 2001-04-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/000000001783986783

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