Trauma-associated growth of suspected dormant micrometastasis

<p>Abstract</p> <p>Background</p> <p>Cancer patients may harbor micrometastases that remain dormant, clinically undetectable during a variable period of time. A traumatic event or surgery may trigger the balance towards tumor growth as a result of associated angiogenesi...

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Bibliographic Details
Main Authors: Geara Fady B, Elhajj Ihab I, El Saghir Nagi S, Hourani Mukbil H
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/94
Description
Summary:<p>Abstract</p> <p>Background</p> <p>Cancer patients may harbor micrometastases that remain dormant, clinically undetectable during a variable period of time. A traumatic event or surgery may trigger the balance towards tumor growth as a result of associated angiogenesis, cytokine and growth factors release.</p> <p>Case presentation</p> <p>We describe a patient with non-small lung cancer who had a rapid tumor growth and recurrence at a minor trauma site of his skull bone.</p> <p>Conclusion</p> <p>This case is an illustration of the phenomenon of tumor growth after trauma or surgery and its associated cellular mechanisms. This phenomenon deserves further investigation and study.</p>
ISSN:1471-2407