Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer
The αvβ3 integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian cancer cells and its potential as a therapeutic target are unknown. In this study, expression of the αvβ3 integrin on ovarian cancer cell lines and murine endothelial cells was tes...
Main Authors: | Charles N. Landen, Tae-Jin Kim, Yvonne G. Lin, William M. Merritt, Aparna A. Kamat, Liz Y. Han, Whitney A. Spannuth, Alpa M. Nick, Nicholas B. Jennnings, Michael S. Kinch, David Tice, Anil K. Sood |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-11-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558608800231 |
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