Site-specific characterization of endogenous SUMOylation across species and organs

Proteomics is a powerful method to study protein SUMOylation, but system-wide insights into endogenous SUMO2/3 modification events are still sparse. Here, the authors develop a more sensitive SUMO proteomics approach, providing detailed maps of endogenous SUMO2/3 sites in human cells and mouse tissu...

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Main Authors:	Ivo A. Hendriks, David Lyon, Dan Su, Niels H. Skotte, Jeremy A. Daniel, Lars J. Jensen, Michael L. Nielsen
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-04957-4

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spelling	doaj-f1a95d5fa715451a8a9764153f666d482021-05-11T10:24:47ZengNature Publishing GroupNature Communications2041-17232018-06-019111710.1038/s41467-018-04957-4Site-specific characterization of endogenous SUMOylation across species and organsIvo A. Hendriks0David Lyon1Dan Su2Niels H. Skotte3Jeremy A. Daniel4Lars J. Jensen5Michael L. Nielsen6Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenDisease Systems Biology Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenProtein Signaling Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenProteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenProtein Signaling Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenDisease Systems Biology Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenProteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of CopenhagenProteomics is a powerful method to study protein SUMOylation, but system-wide insights into endogenous SUMO2/3 modification events are still sparse. Here, the authors develop a more sensitive SUMO proteomics approach, providing detailed maps of endogenous SUMO2/3 sites in human cells and mouse tissues.https://doi.org/10.1038/s41467-018-04957-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ivo A. Hendriks David Lyon Dan Su Niels H. Skotte Jeremy A. Daniel Lars J. Jensen Michael L. Nielsen
spellingShingle	Ivo A. Hendriks David Lyon Dan Su Niels H. Skotte Jeremy A. Daniel Lars J. Jensen Michael L. Nielsen Site-specific characterization of endogenous SUMOylation across species and organs Nature Communications
author_facet	Ivo A. Hendriks David Lyon Dan Su Niels H. Skotte Jeremy A. Daniel Lars J. Jensen Michael L. Nielsen
author_sort	Ivo A. Hendriks
title	Site-specific characterization of endogenous SUMOylation across species and organs
title_short	Site-specific characterization of endogenous SUMOylation across species and organs
title_full	Site-specific characterization of endogenous SUMOylation across species and organs
title_fullStr	Site-specific characterization of endogenous SUMOylation across species and organs
title_full_unstemmed	Site-specific characterization of endogenous SUMOylation across species and organs
title_sort	site-specific characterization of endogenous sumoylation across species and organs
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-06-01
description	Proteomics is a powerful method to study protein SUMOylation, but system-wide insights into endogenous SUMO2/3 modification events are still sparse. Here, the authors develop a more sensitive SUMO proteomics approach, providing detailed maps of endogenous SUMO2/3 sites in human cells and mouse tissues.
url	https://doi.org/10.1038/s41467-018-04957-4
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Site-specific characterization of endogenous SUMOylation across species and organs

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