Ribosomal RNA Transcription Regulation in Breast Cancer

Ribosomal RNA Transcription Regulation in Breast Cancer

Ribosome biogenesis is a complex process that is responsible for the formation of ribosomes and ultimately global protein synthesis. The first step in this process is the synthesis of the ribosomal RNA in the nucleolus, transcribed by RNA Polymerase I. Historically, abnormal nucleolar structure is i...

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Bibliographic Details
Main Authors: Cecelia M. Harold, Amber F. Buhagiar, Yan Cheng, Susan J. Baserga
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
ribosome biogenesis
nucleolus
RNA Polymerase I
rRNA synthesis
breast cancer
Online Access:https://www.mdpi.com/2073-4425/12/4/502

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