Distinguishing linear and branched evolution given single-cell DNA sequencing data of tumors
Abstract Background Cancer arises from an evolutionary process where somatic mutations give rise to clonal expansions. Reconstructing this evolutionary process is useful for treatment decision-making as well as understanding evolutionary patterns across patients and cancer types. In particular, clas...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-07-01
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| Series: | Algorithms for Molecular Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13015-021-00194-5 |