Structural Polymorphism of Chitin and Chitosan in Fungal Cell Walls From Solid-State NMR and Principal Component Analysis

Structural Polymorphism of Chitin and Chitosan in Fungal Cell Walls From Solid-State NMR and Principal Component Analysis

Chitin is a major carbohydrate component of the fungal cell wall and a promising target for novel antifungal agents. However, it is technically challenging to characterize the structure of this polymer in native cell walls. Here, we recorded and compared 13C chemical shifts of chitin using isotopica...

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Bibliographic Details
Main Authors: Liyanage D. Fernando, Malitha C. Dickwella Widanage, Jackson Penfield, Andrew S. Lipton, Nancy Washton, Jean-Paul Latgé, Ping Wang, Liqun Zhang, Tuo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
chitin
chitosan
solid-state NMR
fungi
cell wall
Aspergillus
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.727053/full

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