Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes
Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2017-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00536-1 |
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doaj-f192a5c8e0dd4953a26b536e8ef4f6f92021-05-11T07:30:50ZengNature Publishing GroupNature Communications2041-17232017-09-01811910.1038/s41467-017-00536-1Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexesSanjaya C. Abeysirigunawardena0Hajin Kim1Jonathan Lai2Kaushik Ragunathan3Mollie C. Rappé4Zaida Luthey-Schulten5Taekjip Ha6Sarah A. Woodson7T.C. Jenkins Department of Biophysics, Johns Hopkins UniversitySchool of Life Sciences, Ulsan National Institute of Science and TechnologyDepartment of Chemistry, University of Illinois at Urbana-ChampaignDepartment of Physics, Center for the Physics of Living Cells and Institute for Genomic Biology, University of Illinois at Urbana-ChampaignT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityDepartment of Chemistry, University of Illinois at Urbana-ChampaignT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityT.C. Jenkins Department of Biophysics, Johns Hopkins UniversityRibosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA.https://doi.org/10.1038/s41467-017-00536-1 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson |
| spellingShingle |
Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes Nature Communications |
| author_facet |
Sanjaya C. Abeysirigunawardena Hajin Kim Jonathan Lai Kaushik Ragunathan Mollie C. Rappé Zaida Luthey-Schulten Taekjip Ha Sarah A. Woodson |
| author_sort |
Sanjaya C. Abeysirigunawardena |
| title |
Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_short |
Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_full |
Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_fullStr |
Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_full_unstemmed |
Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes |
| title_sort |
evolution of protein-coupled rna dynamics during hierarchical assembly of ribosomal complexes |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-09-01 |
| description |
Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA. |
| url |
https://doi.org/10.1038/s41467-017-00536-1 |
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