Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)

Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emer...

Full description

Bibliographic Details
Main Authors: Laila Y. AL-Ayadhi, Nadra Elyass Elamin
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/602834
id doaj-f1859a7ae72445438513ea58be8cacd2
record_format Article
spelling doaj-f1859a7ae72445438513ea58be8cacd22020-11-24T23:07:04ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882013-01-01201310.1155/2013/602834602834Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)Laila Y. AL-Ayadhi0Nadra Elyass Elamin1Department of Physiology, Faculty of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi ArabiaAutism Research and Treatment Center, Shaik AL-Amodi Autism Research Chair, Faculty of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi ArabiaExtensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emerged to have potential therapeutic effects in autism. The aim of the current study was to evaluate the effect of camel milk consumption on oxidative stress biomarkers in autistic children, by measuring the plasma levels of glutathione, superoxide dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the ELISA technique. All measured parameters exhibited significant increase after camel milk consumption (). These findings suggest that camel milk could play an important role in decreasing oxidative stress by alteration of antioxidant enzymes and nonenzymatic antioxidant molecules levels, as well as the improvement of autistic behaviour as demonstrated by the improved Childhood Autism Rating Scale (CARS).http://dx.doi.org/10.1155/2013/602834
collection DOAJ
language English
format Article
sources DOAJ
author Laila Y. AL-Ayadhi
Nadra Elyass Elamin
spellingShingle Laila Y. AL-Ayadhi
Nadra Elyass Elamin
Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
Evidence-Based Complementary and Alternative Medicine
author_facet Laila Y. AL-Ayadhi
Nadra Elyass Elamin
author_sort Laila Y. AL-Ayadhi
title Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_short Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_full Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_fullStr Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_full_unstemmed Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_sort camel milk as a potential therapy as an antioxidant in autism spectrum disorder (asd)
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2013-01-01
description Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emerged to have potential therapeutic effects in autism. The aim of the current study was to evaluate the effect of camel milk consumption on oxidative stress biomarkers in autistic children, by measuring the plasma levels of glutathione, superoxide dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the ELISA technique. All measured parameters exhibited significant increase after camel milk consumption (). These findings suggest that camel milk could play an important role in decreasing oxidative stress by alteration of antioxidant enzymes and nonenzymatic antioxidant molecules levels, as well as the improvement of autistic behaviour as demonstrated by the improved Childhood Autism Rating Scale (CARS).
url http://dx.doi.org/10.1155/2013/602834
work_keys_str_mv AT lailayalayadhi camelmilkasapotentialtherapyasanantioxidantinautismspectrumdisorderasd
AT nadraelyasselamin camelmilkasapotentialtherapyasanantioxidantinautismspectrumdisorderasd
_version_ 1725620324336140288