Fighting an old disease with next-generation sequencing

Whole genome sequencing has revealed that most cases of tuberculosis in a high-incidence setting in Malawi were caused by just one lineage of the bacterium responsible for the disease.

Bibliographic Details
Main Authors: Anzaan Dippenaar, Robin M Warren
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06782
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spelling doaj-f1775c2fbf434b33a158e4f71d6a167b2021-05-04T23:40:57ZengeLife Sciences Publications LtdeLife2050-084X2015-03-01410.7554/eLife.06782Fighting an old disease with next-generation sequencingAnzaan Dippenaar0Robin M Warren1DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for TB Research and the Division of Molecular Biology and Human Genetics, Stellenbosch University, Stellenbosch, South AfricaDST/NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for TB Research and the Division of Molecular Biology and Human Genetics, Stellenbosch University, Stellenbosch, South AfricaWhole genome sequencing has revealed that most cases of tuberculosis in a high-incidence setting in Malawi were caused by just one lineage of the bacterium responsible for the disease.https://elifesciences.org/articles/06782tuberculosistransmissionMalawi
collection DOAJ
language English
format Article
sources DOAJ
author Anzaan Dippenaar
Robin M Warren
spellingShingle Anzaan Dippenaar
Robin M Warren
Fighting an old disease with next-generation sequencing
eLife
tuberculosis
transmission
Malawi
author_facet Anzaan Dippenaar
Robin M Warren
author_sort Anzaan Dippenaar
title Fighting an old disease with next-generation sequencing
title_short Fighting an old disease with next-generation sequencing
title_full Fighting an old disease with next-generation sequencing
title_fullStr Fighting an old disease with next-generation sequencing
title_full_unstemmed Fighting an old disease with next-generation sequencing
title_sort fighting an old disease with next-generation sequencing
publisher eLife Sciences Publications Ltd
series eLife
issn 2050-084X
publishDate 2015-03-01
description Whole genome sequencing has revealed that most cases of tuberculosis in a high-incidence setting in Malawi were caused by just one lineage of the bacterium responsible for the disease.
topic tuberculosis
transmission
Malawi
url https://elifesciences.org/articles/06782
work_keys_str_mv AT anzaandippenaar fightinganolddiseasewithnextgenerationsequencing
AT robinmwarren fightinganolddiseasewithnextgenerationsequencing
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