What is the available evidence for the range of applications of genome-editing as a new tool for plant trait modification and the potential occurrence of associated off-target effects: a systematic map

What is the available evidence for the range of applications of genome-editing as a new tool for plant trait modification and the potential occurrence of associated off-target effects: a systematic map

Abstract Background Within the last decades, genome-editing techniques such as CRISPR/Cas, TALENs, Zinc-Finger Nucleases, Meganucleases, Oligonucleotide-Directed Mutagenesis and base editing have been developed enabling a precise modification of DNA sequences. Such techniques provide options for sim...

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Bibliographic Details
Main Authors: Dominik Modrzejewski, Frank Hartung, Thorben Sprink, Dörthe Krause, Christian Kohl, Ralf Wilhelm
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Environmental Evidence
Subjects:
New plant breeding techniques
Gene editing
Targeted genome modification
Mutagenesis
Unintended effects
Off-target mutation
Online Access:http://link.springer.com/article/10.1186/s13750-019-0171-5

Internet

http://link.springer.com/article/10.1186/s13750-019-0171-5

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