Identification of c.1531C&gt;T Pathogenic Variant in the <i>CDH1</i> Gene as a Novel Germline Mutation of Hereditary Diffuse Gastric Cancer

Identification of c.1531C&gt;T Pathogenic Variant in the <i>CDH1</i> Gene as a Novel Germline Mutation of Hereditary Diffuse Gastric Cancer

Germline pathogenic variants in the <i>CDH1</i> gene are a well-established cause of hereditary diffuse gastric cancer (HDGC) syndrome. The aim of this study was to characterize <i>CDH1</i> mutations associated with HDGC from Chile, a country with one of the highest incidence...

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Bibliographic Details
Main Authors: Enrique Norero, M. Alejandra Alarcon, Christopher Hakkaart, Tomas de Mayo, Cecilia Mellado, Marcelo Garrido, Gloria Aguayo, Marcela Lagos, Javiera Torres, Alfonso Calvo, Parry Guilford, Alejandro H. Corvalan
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
hdgc
<i>cdh1</i>
prophylactic gastrectomy
Online Access:https://www.mdpi.com/1422-0067/20/20/4980

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