Microarray Analysis of Glomerular Gene Expression in Murine Lupus Nephritis

To elucidate the molecular mechanism of glomerular events in lupus nephritis, we performed genome-wide mRNA expression analysis of glomeruli microdissected from lupus mice. MRL/lpr mice (12-week-old) were orally given vehicle or prednisolone (10 mg/kg per day) for 4 weeks. Renal histology of MRL/lpr...

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Bibliographic Details
Main Authors: Kae Teramoto, Nobuo Negoro, Kouichirou Kitamoto, Tomoaki Iwai, Hiroshi Iwao, Mikio Okamura, Katsuyuki Miura
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319315361