Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson’s Disease through Activating Mitophagy

Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson’s Disease through Activating Mitophagy

Parkinson’s disease (PD) is a neurodegenerative disease, which is associated with mitochondrial dysfunction and abnormal protein accumulation. No treatment can stop or slow PD. Autophagy inhibits neuronal death by removing damaged mitochondria and abnormal protein aggregations. Celastrol i...

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Bibliographic Details
Main Authors: Ming-Wei Lin, Chi Chien Lin, Yi-Hung Chen, Han-Bin Yang, Shih-Ya Hung
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Antioxidants
Subjects:
autophagy
celastrol
dopaminergic neurons
mitophagy
parkinson’s disease
Online Access:https://www.mdpi.com/2076-3921/9/1/37

Internet

https://www.mdpi.com/2076-3921/9/1/37

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