Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism.

Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism.

Transmissible spongiform encephalopathies are neurodegenerative diseases, which despite fervent research remain incurable. Immunization approaches have shown great potential at providing protection, however tolerance effects hamper active immunization protocols. In this study we evaluated the antige...

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Bibliographic Details
Main Authors: Konstantinos Xanthopoulos, Rosa Lagoudaki, Anastasia Kontana, Christos Kyratsous, Christos Panagiotidis, Nikolaos Grigoriadis, Minas Yiangou, Theodoros Sklaviadis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3598700?pdf=render

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http://europepmc.org/articles/PMC3598700?pdf=render

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