Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump

Objective: The aim of this study was to identify pulmonary dysfunction and factors associated with prolonged mechanical ventilation, hospital stay, weaning failure and mortality in patients undergoing coronary artery bypass grafting with use of intra-aortic balloon pump (IABP). Methods: This observa...

Full description

Bibliographic Details
Main Authors: Helena Amaral Gonçalves Fusatto, Luciana Castilho de Figueiredo, Ana Paula Ragonete dos Anjos Agostini, Melissa Sibinelli, Desanka Dragosavac
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Revista Portuguesa de Cardiologia (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2174204918300060
id doaj-f14849a1f71b478786bfb2ff9a5111f2
record_format Article
spelling doaj-f14849a1f71b478786bfb2ff9a5111f22020-11-24T21:43:28ZengElsevierRevista Portuguesa de Cardiologia (English Edition)2174-20492018-01-013711523Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pumpHelena Amaral Gonçalves Fusatto0Luciana Castilho de Figueiredo1Ana Paula Ragonete dos Anjos Agostini2Melissa Sibinelli3Desanka Dragosavac4Faculdade Anhanguera de Piracicaba, Piracicaba, BrazilHospital das Clínicas da UNICAMP, Campinas, BrazilUniversidade Estadual de Campinas, Campinas, Brazil; Corresponding author.Hospital das Clínicas da UNICAMP, Campinas, BrazilUniversidade Estadual de Campinas, Campinas, BrazilObjective: The aim of this study was to identify pulmonary dysfunction and factors associated with prolonged mechanical ventilation, hospital stay, weaning failure and mortality in patients undergoing coronary artery bypass grafting with use of intra-aortic balloon pump (IABP). Methods: This observational study analyzed respiratory, surgical, clinical and demographic variables and related them to outcomes. Results: We analyzed 39 patients with a mean age of 61.2 years. Pulmonary dysfunction, characterized by mildly impaired gas exchange, was present from the immediate postoperative period to the third postoperative day. Mechanical ventilation time was influenced by the use of IABP and PaO2/FiO2, female gender and smoking. Intensive care unit (ICU) stay was influenced by APACHE II score and use of IABP. Mortality was strongly influenced by APACHE II score, followed by weaning failure. Conclusion: Pulmonary dysfunction was present from the first to the third postoperative day. Mechanical ventilation time was influenced by female gender, smoking, duration of IABP use and PaO2/FiO2 on the first postoperative day. ICU stay was influenced by APACHE II score and duration of IABP. Mortality was influenced by APACHE II score, followed by weaning failure. Resumo: Objetivo: O objetivo deste estudo foi identificar a disfunção pulmonar e fatores relacionados ao tempo de ventilação mecânica e internação, insucesso da extubação e mortalidade em pacientes submetidos à cirurgia de revascularização de miocárdio, com uso de balão intra-aórtico. Método: Estudo observacional, no qual foram analisadas variáveis respiratórias, clínico-demográficas e cirúrgicas que, posteriormente, foram relacionadas com os desfechos. Resultados: Foram avaliados 39 pacientes, com idade média 61,2 anos. A disfunção pulmonar esteve presente do pós operatório imediato (POI) ao PO3, caracterizada por DTTG de grau leve. A ventilação mecânica apresentou influência do tempo de uso do balão intra-aórtico, PaO2/FiO2, sexo feminino e o tabagismo. A internação na UTI foi influenciada pelo APACHE II e uso de balão intra-aórtico. O óbito apresentou influência do APACHE II, seguido do insucesso da extubação. Conclusão: A disfunção pulmonar esteve presente do POI até o PO3. O tempo de VM foi influenciado pelo sexo feminino, tabagismo, tempo BIA e PaO2/FiO2 no POI. O tempo de internação foi influenciado pelo APACHE II e uso do balão intra-aórtico. A mortalidade foi influenciada pelo APACHE II, seguido do insucesso de desmame. Keywords: Myocardial revascularization, Intra-aortic balloon pump, Postoperative complications, Length of stay, Intensive care units, Palavras-chave: Revascularização miocárdica, Balão intra-aórtico, Complicações pós-operatórias, Tempo de internação, Unidades de terapia intensivahttp://www.sciencedirect.com/science/article/pii/S2174204918300060
collection DOAJ
language English
format Article
sources DOAJ
author Helena Amaral Gonçalves Fusatto
Luciana Castilho de Figueiredo
Ana Paula Ragonete dos Anjos Agostini
Melissa Sibinelli
Desanka Dragosavac
spellingShingle Helena Amaral Gonçalves Fusatto
Luciana Castilho de Figueiredo
Ana Paula Ragonete dos Anjos Agostini
Melissa Sibinelli
Desanka Dragosavac
Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
Revista Portuguesa de Cardiologia (English Edition)
author_facet Helena Amaral Gonçalves Fusatto
Luciana Castilho de Figueiredo
Ana Paula Ragonete dos Anjos Agostini
Melissa Sibinelli
Desanka Dragosavac
author_sort Helena Amaral Gonçalves Fusatto
title Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
title_short Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
title_full Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
title_fullStr Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
title_full_unstemmed Factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
title_sort factors associated with pulmonary dysfunction in patients undergoing coronary artery bypass graft surgery with use of intra-aortic balloon pump
publisher Elsevier
series Revista Portuguesa de Cardiologia (English Edition)
issn 2174-2049
publishDate 2018-01-01
description Objective: The aim of this study was to identify pulmonary dysfunction and factors associated with prolonged mechanical ventilation, hospital stay, weaning failure and mortality in patients undergoing coronary artery bypass grafting with use of intra-aortic balloon pump (IABP). Methods: This observational study analyzed respiratory, surgical, clinical and demographic variables and related them to outcomes. Results: We analyzed 39 patients with a mean age of 61.2 years. Pulmonary dysfunction, characterized by mildly impaired gas exchange, was present from the immediate postoperative period to the third postoperative day. Mechanical ventilation time was influenced by the use of IABP and PaO2/FiO2, female gender and smoking. Intensive care unit (ICU) stay was influenced by APACHE II score and use of IABP. Mortality was strongly influenced by APACHE II score, followed by weaning failure. Conclusion: Pulmonary dysfunction was present from the first to the third postoperative day. Mechanical ventilation time was influenced by female gender, smoking, duration of IABP use and PaO2/FiO2 on the first postoperative day. ICU stay was influenced by APACHE II score and duration of IABP. Mortality was influenced by APACHE II score, followed by weaning failure. Resumo: Objetivo: O objetivo deste estudo foi identificar a disfunção pulmonar e fatores relacionados ao tempo de ventilação mecânica e internação, insucesso da extubação e mortalidade em pacientes submetidos à cirurgia de revascularização de miocárdio, com uso de balão intra-aórtico. Método: Estudo observacional, no qual foram analisadas variáveis respiratórias, clínico-demográficas e cirúrgicas que, posteriormente, foram relacionadas com os desfechos. Resultados: Foram avaliados 39 pacientes, com idade média 61,2 anos. A disfunção pulmonar esteve presente do pós operatório imediato (POI) ao PO3, caracterizada por DTTG de grau leve. A ventilação mecânica apresentou influência do tempo de uso do balão intra-aórtico, PaO2/FiO2, sexo feminino e o tabagismo. A internação na UTI foi influenciada pelo APACHE II e uso de balão intra-aórtico. O óbito apresentou influência do APACHE II, seguido do insucesso da extubação. Conclusão: A disfunção pulmonar esteve presente do POI até o PO3. O tempo de VM foi influenciado pelo sexo feminino, tabagismo, tempo BIA e PaO2/FiO2 no POI. O tempo de internação foi influenciado pelo APACHE II e uso do balão intra-aórtico. A mortalidade foi influenciada pelo APACHE II, seguido do insucesso de desmame. Keywords: Myocardial revascularization, Intra-aortic balloon pump, Postoperative complications, Length of stay, Intensive care units, Palavras-chave: Revascularização miocárdica, Balão intra-aórtico, Complicações pós-operatórias, Tempo de internação, Unidades de terapia intensiva
url http://www.sciencedirect.com/science/article/pii/S2174204918300060
work_keys_str_mv AT helenaamaralgoncalvesfusatto factorsassociatedwithpulmonarydysfunctioninpatientsundergoingcoronaryarterybypassgraftsurgerywithuseofintraaorticballoonpump
AT lucianacastilhodefigueiredo factorsassociatedwithpulmonarydysfunctioninpatientsundergoingcoronaryarterybypassgraftsurgerywithuseofintraaorticballoonpump
AT anapaularagonetedosanjosagostini factorsassociatedwithpulmonarydysfunctioninpatientsundergoingcoronaryarterybypassgraftsurgerywithuseofintraaorticballoonpump
AT melissasibinelli factorsassociatedwithpulmonarydysfunctioninpatientsundergoingcoronaryarterybypassgraftsurgerywithuseofintraaorticballoonpump
AT desankadragosavac factorsassociatedwithpulmonarydysfunctioninpatientsundergoingcoronaryarterybypassgraftsurgerywithuseofintraaorticballoonpump
_version_ 1725913976933449728