Age-associated hyper-methylated regions in the human brain overlap with bivalent chromatin domains.

Recent associations between age-related differentially methylated sites and bivalently marked chromatin domains have implicated a role for these genomic regions in aging and age-related diseases. However, the overlap between such epigenetic modifications has so far only been identified with respect...

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Bibliographic Details
Main Authors: Corey T Watson, Giulio Disanto, Geir Kjetil Sandve, Felix Breden, Gavin Giovannoni, Sreeram V Ramagopalan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454416?pdf=render