Ferroptosis and Cancer: Mitochondria Meet the “Iron Maiden” Cell Death
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent lipid peroxidation. As major sites of iron utilization and master regulators of oxidative metabolism, mitochondria are the main source of reactive oxygen species (ROS) and, thus, play a role in this type of RC...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/6/1505 |