A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames

<p>Abstract</p> <p>CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesized that such escape is made more difficult if the imm...

Full description

Bibliographic Details
Main Authors: Marx Preston A, Blauvelt Andrew, Donio Michael J, Klase Zachary, Jeang Kuan-Teh, Smith Stephen M
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/1