Rapid decline of kidney function in diabetic kidney disease is associated with high soluble Klotho levels

Background: Klotho is found in two forms: a transmembrane form and a soluble form (s-Klotho). In order to be excreted, s-Klotho, that is too large to be filtered, will probably reach the proximal convoluted tubule by a transcytosis process. The aim of our study was to show the relationship between t...

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Bibliographic Details
Main Authors: Flaviu Bob, Adalbert Schiller, Romulus Timar, Daniel Lighezan, Oana Schiller, Bogdan Timar, Cristiana Georgeta Bujor, Mircea Munteanu, Florica Gadalean, Adelina Mihaescu, Iulia Grosu, Andreea Hategan, Lazar Chisavu, Agneta-Maria Pusztai, Adrian Covic
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Nefrología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251419300677