Topology, Antiviral Functional Residues and Mechanism of IFITM1

Topology, Antiviral Functional Residues and Mechanism of IFITM1

Interferon-inducible transmembrane proteins (IFITM1/2/3) have been reported to suppress the entry of a wide range of viruses. However, their antiviral functional residues and specific mechanisms are still unclear. Here, we firstly resolved the topology of IFITM1 on the plasma membrane where N-termin...

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Bibliographic Details
Main Authors: Fang Sun, Zhiqiang Xia, Yuewen Han, Minjun Gao, Luyao Wang, Yingliang Wu, Jean-Marc Sabatier, Lixia Miao, Zhijian Cao
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Viruses
Subjects:
ifitm1
topology
antiviral functional residues
mechanism
Online Access:https://www.mdpi.com/1999-4915/12/3/295

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