Be Cautious with Crystal Structures of Membrane Proteins or Complexes Prepared in Detergents

Membrane proteins are an important class of macromolecules found in all living organisms and many of them serve as important drug targets. In order to understand their biological and biochemical functions and to exploit them for structure-based drug design, high-resolution and accurate structures of...

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Bibliographic Details
Main Author: Youzhong Guo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/10/2/86