Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent

Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent

HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R) were quantitated in plasma from rats and beag...

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Bibliographic Details
Main Authors: In Yong Bae, Min Sun Choi, Young Seok Ji, Sang-Ku Yoo, Kyungil Kim, Hye Hyun Yoo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
hsg4112
anti-obesity agent
stereoselectivity
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/12/2/127

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https://www.mdpi.com/1999-4923/12/2/127

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