Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome
We previously reported that the highly reactive cell-free heme (CFH) is increased in the plasma of patients with chronic lung injury and causes pulmonary edema in animal model of acute respiratory distress syndrome (ARDS) post inhalation of halogen gas. However, the mechanisms by which CFH causes pu...
Main Authors: | Saurabh Aggarwal, Ahmed Lazrak, Israr Ahmad, Zhihong Yu, Ayesha Bryant, James A. Mobley, David A. Ford, Sadis Matalon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720304894 |
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