TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.

PWWP domains are involved in the chromatin attachment of several proteins. They bind to both DNA and proteins and their interaction with specific histone methylation marks define them as a new class of histone code readers. The lens epithelium derived growth factor (LEDGF/p75) contains an N-terminal...

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Bibliographic Details
Main Authors: Mehdi Morchikh, Monica Naughtin, Francesca Di Nunzio, Johan Xavier, Pierre Charneau, Yves Jacob, Marc Lavigne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312278/?tool=EBI

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