Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity.

Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity.

Prevention of an immune response against self-antigens derived from apoptotic cells is essential to preclude autoimmune and chronic inflammatory diseases. Here, we describe apoptosis induced externalization of endogenous cytosolic annexin 1 initiating an anti-inflammatory effector mechanism that sup...

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Bibliographic Details
Main Authors: Heiko Weyd, Lucie Abeler-Dörner, Björn Linke, Andrea Mahr, Veronika Jahndel, Sandra Pfrang, Martina Schnölzer, Christine S Falk, Peter H Krammer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3640057?pdf=render

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