Relevance of Pharmacogenomics and Multidisciplinary Management in a Young-Elderly Patient With KRAS Mutant Colorectal Cancer Treated With First-Line Aflibercept-Containing Chemotherapy

Relevance of Pharmacogenomics and Multidisciplinary Management in a Young-Elderly Patient With KRAS Mutant Colorectal Cancer Treated With First-Line Aflibercept-Containing Chemotherapy

Introduction: Intensive oncological treatment integrated with resection of metastases raised the clinical outcome of metastatic colorectal cancer (MCRC). In clinical practice, complex evaluation of clinical (age, performance status, comorbidities), and biological (tumoral genotype, pharmacogenomic)...

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Bibliographic Details
Main Authors: Gemma Bruera, Antonio D'Andrilli, Maurizio Simmaco, Stefano Guadagni, Erino Angelo Rendina, Enrico Ricevuto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
aflibercept/chemotherapy
case report
young-elderly unfit MCRC
multidisciplinary management
pharmacogenomic analyses
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01155/full

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