The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively

The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively

Minimal residual disease (MRD) is now a powerful surrogate marker to assess the response to chemotherapy in acute myeloid leukemia (AML). <i>DNMT3A</i> mutation has been associated with adverse outcomes. In this study, we aimed to investigate the impact of <i>DNMT3A</i> statu...

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Bibliographic Details
Main Authors: Heiblig Maël, Duployez Nicolas, Marceau Alice, Lebon Delphine, Goursaud Laure, Plantier Isabelle, Stalnikiewich Laure, Cambier Nathalie, Balsat Marie, Fossard Gaëlle, Labussière-Wallet Hélène, Barraco Fiorenza, Ducastelle-Lepretre Sophie, Sujobert Pierre, Huet Sarah, Hayette Sandrine, Ghesquières Hervé, Thomas Xavier, Preudhomme Claude
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
acute myeloid leukemia
elderly
prognosis
<i>NPM1</i>
<i>DNMT3A</i>
Online Access:https://www.mdpi.com/2072-6694/13/9/2156

Internet

https://www.mdpi.com/2072-6694/13/9/2156

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