New Strategies for Treatment of Sepsis

Sepsis represents a major global health concern and is one of the most feared complications for hospitalized patients, being the cause, directly or indirectly, of about half of all hospital deaths. According to the last definition, sepsis is a life-threatening organ dysfunction caused by a dysregula...

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Main Authors: Antonio Mirijello, Alberto Tosoni, on behalf of the Internal Medicine Sepsis Study Group
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/56/10/527
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spelling doaj-f0f56f298e44443ea73428add72bd1ac2020-11-25T04:00:23ZengMDPI AGMedicina1010-660X2020-10-015652752710.3390/medicina56100527New Strategies for Treatment of SepsisAntonio Mirijello0Alberto Tosoni1on behalf of the Internal Medicine Sepsis Study GroupInternal Medicine Unit, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, ItalyDepartment of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, ItalySepsis represents a major global health concern and is one of the most feared complications for hospitalized patients, being the cause, directly or indirectly, of about half of all hospital deaths. According to the last definition, sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and defined septic shock as a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are profound enough to significantly increase mortality. Sepsis is a time-dependent disease and requires a prompt recognition and a standardized treatment. The Special Issue “New Strategies for Treatment of Sepsis” has been thought to connect the experience of physicians involved in the diagnosis, management, and treatment of sepsis at every stage of disease, from emergency departments to general and intensive wards. The focus will be pointed on new approaches to this syndrome, such as early recognition based on clinical features and biomarkers, management in non-ICUs, non-invasive treatment strategies, including non-antimicrobial agents, and, of course, invasive approaches. This Special Issue will highlight the many different facets of sepsis, seen through the eyes of different specialists. We hope to spread the knowledge of a new blueprint for treatment.https://www.mdpi.com/1010-660X/56/10/527internal medicineintensive careemergency departmentorgan dysfunctionimmunomodulationmicronutrients
collection DOAJ
language English
format Article
sources DOAJ
author Antonio Mirijello
Alberto Tosoni
on behalf of the Internal Medicine Sepsis Study Group
spellingShingle Antonio Mirijello
Alberto Tosoni
on behalf of the Internal Medicine Sepsis Study Group
New Strategies for Treatment of Sepsis
Medicina
internal medicine
intensive care
emergency department
organ dysfunction
immunomodulation
micronutrients
author_facet Antonio Mirijello
Alberto Tosoni
on behalf of the Internal Medicine Sepsis Study Group
author_sort Antonio Mirijello
title New Strategies for Treatment of Sepsis
title_short New Strategies for Treatment of Sepsis
title_full New Strategies for Treatment of Sepsis
title_fullStr New Strategies for Treatment of Sepsis
title_full_unstemmed New Strategies for Treatment of Sepsis
title_sort new strategies for treatment of sepsis
publisher MDPI AG
series Medicina
issn 1010-660X
publishDate 2020-10-01
description Sepsis represents a major global health concern and is one of the most feared complications for hospitalized patients, being the cause, directly or indirectly, of about half of all hospital deaths. According to the last definition, sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and defined septic shock as a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are profound enough to significantly increase mortality. Sepsis is a time-dependent disease and requires a prompt recognition and a standardized treatment. The Special Issue “New Strategies for Treatment of Sepsis” has been thought to connect the experience of physicians involved in the diagnosis, management, and treatment of sepsis at every stage of disease, from emergency departments to general and intensive wards. The focus will be pointed on new approaches to this syndrome, such as early recognition based on clinical features and biomarkers, management in non-ICUs, non-invasive treatment strategies, including non-antimicrobial agents, and, of course, invasive approaches. This Special Issue will highlight the many different facets of sepsis, seen through the eyes of different specialists. We hope to spread the knowledge of a new blueprint for treatment.
topic internal medicine
intensive care
emergency department
organ dysfunction
immunomodulation
micronutrients
url https://www.mdpi.com/1010-660X/56/10/527
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