Profound Differences in Virus Population Genetics Correspond to Protection from CD4 Decline Resulting from Feline Lentivirus Coinfection

Profound Differences in Virus Population Genetics Correspond to Protection from CD4 Decline Resulting from Feline Lentivirus Coinfection

CD4 decline is a hallmark of disease onset in individuals infected with Feline Immunodeficiency Virus (FIV) or Human Immunodeficiency Virus type 1 (HIV-1). Cats that are infected with a poorly replicating, apathogenic FIV (PLV) prior to exposure to a virulent FIV strain (FIVC) maintain CD4 numbers b...

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Bibliographic Details
Main Authors: Abinash Padhi, Howard Ross, Julie Terwee, Mary Poss, Sue VandeWoude
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Viruses
Subjects:
Lentivirus
dual infection
population genetics
genetic bottleneck
viral temporal dynamics
mutation rate
Online Access:http://www.mdpi.com/1999-4915/2/12/2663/

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