A Metabolic Obesity Profile Is Associated With Decreased Gray Matter Volume in Cognitively Healthy Older Adults

A Metabolic Obesity Profile Is Associated With Decreased Gray Matter Volume in Cognitively Healthy Older Adults

Obesity is a risk factor for cognitive decline and gray matter volume loss in aging. Studies have shown that different metabolic factors, e.g., dysregulated glucose metabolism and systemic inflammation, might mediate this association. Yet, even though these risk factors tend to co-occur, they have m...

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Bibliographic Details
Main Authors: Frauke Beyer, Shahrzad Kharabian Masouleh, Jürgen Kratzsch, Matthias L. Schroeter, Susanne Röhr, Steffi G. Riedel-Heller, Arno Villringer, A. Veronica Witte
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
obesity
leptin – adiponectin
aging
metabolic risk
multivariate analysis
VBM
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00202/full

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